Targeted drug delivery systems for matrix metalloproteinase-responsive anoparticles in tumor cells: A review

F Guo, Y Du, Y Wang, M Wang, L Wang, N Yu… - International Journal of …, 2023 - Elsevier
… responses have shown excellent performance in tumor-targeted therapy, given their unique
targeting and drug-release characteristics. Matrix metalloproteinases (MMPs) have been …

Enzyme-responsive nano-drug delivery system for combined antitumor therapy

F Guo, Y Jiao, Y Du, S Luo, W Hong, Q Fu, A Li… - International journal of …, 2022 - Elsevier
… -loaded matrix metalloproteinase (MMP)-responsive nanoparticles (… These nanoparticles
combine the properties of both PEG-peptides … Curcumin-loaded MMP-responsive nanoparticles

Endogenous enzyme-responsive nanoplatforms for anti-tumor therapy

XF Lou, YZ Du, XL Xu - Current Drug Targets, 2021 - ingentaconnect.com
treated with this paclitaxel-loaded nanoparticle demonstrated only a 1.9-fold volume
increase after 24 days, while the free paclitaxel-treated group and non-sensitive nanoparticles

[HTML][HTML] Natural ingredient-based polymeric nanoparticles for cancer treatment

KH Wong, A Lu, X Chen, Z Yang - Molecules, 2020 - mdpi.com
… With the aid of a magnetic field, targeted delivery of curcumin by the nanoparticle system
was achieved. Curcumin-loaded nanoparticles showed stronger cytotoxicity to the breast …

Advances in preparation, interaction and stimulus responsiveness of protein-based nanodelivery systems

Q Lin, S Ge, DJ McClements, X Li, Z Jin… - Critical Reviews in …, 2023 - Taylor & Francis
… Core-shell curcumin-loaded nanocarriers have also been formed using a combination of …
Initially, curcumin-loaded zein nanoparticles are formed by antisolvent precipitation and then …

[HTML][HTML] Pharmacokinetics of Curcumin Delivered by Nanoparticles and the Relationship with Antitumor Efficacy: A Systematic Review

F Silvestre, C Santos, V Silva, A Ombredane… - Pharmaceuticals, 2023 - mdpi.com
… The curcumin-loaded nanoparticles could be implemented for overcoming their poor …
demonstrates that metalloproteinase-responsive curcumin-loaded nanoparticles inhibited …

[HTML][HTML] Targeted exosome-based nanoplatform for new-generation therapeutic strategies

W Yin, H Ma, Y Qu, S Wang, R Zhao, Y Yang… - Biomedical …, 2024 - iopscience.iop.org
… the targeted delivery of curcumin-loaded exosomes to glioma (figure 4(… potential as drug
carriers for tumor targeted drug delivery. … for the matrix metalloproteinase-responsive therapeutic …

Star polyester-based folate acid-targeting nanoparticles for doxorubicin and curcumin co-delivery to combat multidrug-resistant breast cancer

F Guo, N Yu, Y Jiao, W Hong, K Zhou, X Ji, H Yuan… - Drug Delivery, 2021 - Taylor & Francis
Chemotherapeutic treatments are indispensable in the treatment of breast cancer. However,
the emergence of multidrug-resistance, strong cell toxicity, and poor targeting selection has …

Dual-targeted enzyme-sensitive hyaluronic acid nanogels loading paclitaxel for the therapy of breast cancer

D Gao, S Asghar, J Ye, M Zhang, R Hu, Y Wang… - Carbohydrate …, 2022 - Elsevier
In this study, a CD44 and biotin receptors dual-targeted enzyme-sensitive hyaluronic acid
nanogel loading paclitaxel (PTX/Bio-NG) for targeting breast cancer was constructed. …

[HTML][HTML] Delivery of natural agents by means of mesoporous silica nanospheres as a promising anticancer strategy

K AbouAitah, W Lojkowski - Pharmaceutics, 2021 - mdpi.com
… [228] tailored a co-delivery system of Dox loaded into MSNs as the core and curcumin loaded
into the polymeric coating shell. The results indicate the long duration of blood circulation …